Neural correlates of sensorimotor gating: A metabolic positron emission tomography study in awake rats

Neural correlates of sensorimotor gating: A metabolic positron emission tomography study in awake rats

Impaired sensorimotor gating occurs in neuropsychiatric disorders such as schizophrenia and can be measured using the prepulse inhibition (PPI) paradigm of the acoustic startle response. This assay is frequently used to validate animal models of neuropsychiatric disorders and to explore the therapeu...

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Bibliographic Details
Main Authors: Cathrin eRohleder, Fabienne eJung, Hanna eMertgens, Dirk eWiedermann, Michael eSué, Bernd eNeumaier, Rudolf eGraf, F. Markus eLeweke, Heike eEndepols
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Neural Network
prepulse inhibition
neuropsychiatric disorders
startle
Translational research
FDG-PET
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00178/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00178/full

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