A High-Through Technique to Measure DNA Methylation

MethyLight is a sodium-bisulfite-dependent, quantitative, fluorescence-based, real-time PCR strategy that is used to detect and quantify DNA methylation in genomic DNA. High-throughput MethyLight allows the rapid and sensitive detection of very low frequencies of hypermethylated alleles in populatio...

Full description

Bibliographic Details
Main Authors: Zhiming Zhang, Jian Gao, Cheng Qin, Li Liu, Haijian Lin, Yaou Shen, Shibin Gao, Maojun Zhao, Haiping Ding, Guangtang Pan
Format: Article
Language:English
Published: SAGE Publishing 2010-01-01
Series:Genetics and Epigenetics
Online Access:https://doi.org/10.4137/GEG.S5035