How Soluble GARP Enhances TGFβ Activation.

GARP (glycoprotein A repetitions predominant) is a cell surface receptor on regulatory T-lymphocytes, platelets, hepatic stellate cells and certain cancer cells. Its described function is the binding and accommodation of latent TGFβ (transforming growth factor), before the activation and release of...

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Bibliographic Details
Main Authors: Sven Fridrich, Susanne A Hahn, Marion Linzmaier, Matthias Felten, Jenny Zwarg, Volker Lennerz, Andrea Tuettenberg, Walter Stöcker
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4824412?pdf=render