Mediation by differential DNA methylation of known associations between single nucleotide polymorphisms and bladder cancer risk

Mediation by differential DNA methylation of known associations between single nucleotide polymorphisms and bladder cancer risk

Abstract Background Though bladder cancer has been the subject of many well-powered genome-wide association studies, the mechanisms involving bladder-cancer-associated single nucleotide polymorphisms (SNPs) remain largely unknown. This study focuses on rs798766, rs401681, rs2294008, and rs8102137, w...

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Bibliographic Details
Main Authors: Kristina M. Jordahl, Amanda I. Phipps, Timothy W. Randolph, Lesley F. Tinker, Rami Nassir, Lifang Hou, Garnet L. Anderson, Karl T. Kelsey, Emily White, Parveen Bhatti
Format: Article
Language:English
Published: BMC 2020-11-01
Series:BMC Medical Genetics
Subjects:
Bladder cancer risk SNPs
DNA methylation
Bladder cancer
Mediation analysis
Online Access:http://link.springer.com/article/10.1186/s12881-020-01172-1

Internet

http://link.springer.com/article/10.1186/s12881-020-01172-1

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