Phenotypic Plasticity of Fibroblasts during Mammary Carcinoma Development

Phenotypic Plasticity of Fibroblasts during Mammary Carcinoma Development

Cancer-associated fibroblasts (CAFs) in the tumor microenvironment contribute to all stages of tumorigenesis and are usually considered to be tumor-promoting cells. CAFs show a remarkable degree of heterogeneity, which is attributed to developmental origin or to local environmental niches, resulting...

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Bibliographic Details
Main Authors: Eiman Elwakeel, Mirko Brüggemann, Annika F. Fink, Marcel H. Schulz, Tobias Schmid, Rajkumar Savai, Bernhard Brüne, Kathi Zarnack, Andreas Weigert
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:International Journal of Molecular Sciences
Subjects:
cancer-associated fibroblasts
mammary carcinoma
cancer
transcriptional profiling
gene signature
Online Access:https://www.mdpi.com/1422-0067/20/18/4438

Internet

https://www.mdpi.com/1422-0067/20/18/4438

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