Arp2/3 complex activity in filopodia of spreading cells

<p>Abstract</p> <p>Background</p> <p>Cells use filopodia to explore their environment and to form new adhesion contacts for motility and spreading. The Arp2/3 complex has been implicated in lamellipodial actin assembly as a major nucleator of new actin filaments in bran...

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Bibliographic Details
Main Authors: Mendes Paula M, Yeung Chun L, Bramble Jonathan P, Johnston Simon A, Machesky Laura M
Format: Article
Language:English
Published: BMC 2008-12-01
Series:BMC Cell Biology
Online Access:http://www.biomedcentral.com/1471-2121/9/65