Delta-Like Protein 3 Expression in Paired Chemonaive and Chemorelapsed Small Cell Lung Cancer Samples

Delta-Like Protein 3 Expression in Paired Chemonaive and Chemorelapsed Small Cell Lung Cancer Samples

Rovalpituzumab tesirine (Rova-T), an antibody-drug conjugate directed against Delta-like protein 3 (DLL3), is under development for patients with small cell lung cancer (SCLC). DLL3 is expressed on the majority of SCLC samples. Because SCLC is rarely biopsied in the course of disease, data regarding...

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Bibliographic Details
Main Authors: Christiane Kuempers, Tobias Jagomast, Rosemarie Krupar, Finn-Ole Paulsen, Carsten Heidel, Julika Ribbat-Idel, Christian Idel, Bruno Märkl, Martin Anlauf, Sabina Berezowska, Markus Tiemann, Hans Bösmüller, Falko Fend, Barbara Kalsdorf, Sabine Bohnet, Eva Dreyer, Verena Sailer, Jutta Kirfel, Sven Perner
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Medicine
Subjects:
delta-like protein 3
small cell lung cancer
paired
chemonaive
chemorelapsed
Online Access:https://www.frontiersin.org/articles/10.3389/fmed.2021.734901/full

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https://www.frontiersin.org/articles/10.3389/fmed.2021.734901/full

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