MiR-200c-3p Contrasts PD-L1 Induction by Combinatorial Therapies and Slows Proliferation of Epithelial Ovarian Cancer through Downregulation of β-Catenin and c-Myc

MiR-200c-3p Contrasts PD-L1 Induction by Combinatorial Therapies and Slows Proliferation of Epithelial Ovarian Cancer through Downregulation of β-Catenin and c-Myc

Conventional/targeted chemotherapies and ionizing radiation (IR) are being used both as monotherapies and in combination for the treatment of epithelial ovarian cancer (EOC). Several studies show that these therapies might favor oncogenic signaling and impede anti-tumor responses. MiR-200c is consid...

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Bibliographic Details
Main Authors: Eleni Anastasiadou, Elena Messina, Tiziana Sanavia, Lucia Mundo, Federica Farinella, Stefano Lazzi, Francesca Megiorni, Simona Ceccarelli, Paola Pontecorvi, Francesco Marampon, Cira Rosaria Tiziana Di Gioia, Giorgia Perniola, Pierluigi Benedetti Panici, Lorenzo Leoncini, Pankaj Trivedi, Andrea Lenzi, Cinzia Marchese
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Cells
Subjects:
epithelial ovarian cancer
immune checkpoints
PARPi
ionizing radiation
miRNA-based therapy
Online Access:https://www.mdpi.com/2073-4409/10/3/519

Internet

https://www.mdpi.com/2073-4409/10/3/519

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