Detecting functional divergence after gene duplication through evolutionary changes in posttranslational regulatory sequences.

Gene duplication is an important evolutionary mechanism that can result in functional divergence in paralogs due to neo-functionalization or sub-functionalization. Consistent with functional divergence after gene duplication, recent studies have shown accelerated evolution in retained paralogs. Howe...

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Bibliographic Details
Main Authors: Alex N Nguyen Ba, Bob Strome, Jun Jie Hua, Jonathan Desmond, Isabelle Gagnon-Arsenault, Eric L Weiss, Christian R Landry, Alan M Moses
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-12-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4256066?pdf=render