Peripheral Sensory Deprivation Restores Critical-Period-like Plasticity to Adult Somatosensory Thalamocortical Inputs

Peripheral Sensory Deprivation Restores Critical-Period-like Plasticity to Adult Somatosensory Thalamocortical Inputs

Recent work has shown that thalamocortical (TC) inputs can be plastic after the developmental critical period has closed, but the mechanism that enables re-establishment of plasticity is unclear. Here, we find that long-term potentiation (LTP) at TC inputs is transiently restored in spared barrel co...

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Bibliographic Details
Main Authors: Seungsoo Chung, Ji-Hyun Jeong, Sukjin Ko, Xin Yu, Young-Hwan Kim, John T.R. Isaac, Alan P. Koretsky
Format: Article
Language:English
Published: Elsevier 2017-06-01
Series:Cell Reports
Subjects:
glutamate
long-term potentiation
NMDA receptor
synaptic plasticity
adult barrel cortex
experience-dependent plasticity
silent synapses
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471730815X

Internet

http://www.sciencedirect.com/science/article/pii/S221112471730815X

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