MiR-27a targets sFRP1 in hFOB cells to regulate proliferation, apoptosis and differentiation.

MicroRNAs (miRNAs) play a key role in the regulation of almost all the physiological and pathological processes, including bone metabolism. Recent studies have suggested that miR-27 might play a key role in osteoblast differentiation and bone formation. Increasing evidence indicates that the canonic...

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Bibliographic Details
Main Authors: Donggeng Guo, Qiuxia Li, Qing Lv, Qiujing Wei, Shuangyan Cao, Jieruo Gu
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3953332?pdf=render