β-Caryophyllene, a CB2-Receptor-Selective Phytocannabinoid, Suppresses Mechanical Allodynia in a Mouse Model of Antiretroviral-Induced Neuropathic Pain

β-Caryophyllene, a CB2-Receptor-Selective Phytocannabinoid, Suppresses Mechanical Allodynia in a Mouse Model of Antiretroviral-Induced Neuropathic Pain

Neuropathic pain associated with nucleoside reverse transcriptase inhibitors (NRTIs), therapeutic agents for human immunodeficiency virus (HIV), responds poorly to available drugs. Smoked cannabis was reported to relieve HIV-associated neuropathic pain in clinical trials. Some constituents of cannab...

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Bibliographic Details
Main Authors: Esraa Aly, Maitham A. Khajah, Willias Masocha
Format: Article
Language:English
Published: MDPI AG 2019-12-01
Series:Molecules
Subjects:
neuropathic pain
nucleoside reverse transcriptase inhibitor
cytokines
ddc
phytocannabinoid
β-caryophyllene
antiretroviral
mechanical allodynia
cb2 receptor
Online Access:https://www.mdpi.com/1420-3049/25/1/106

Internet

https://www.mdpi.com/1420-3049/25/1/106

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