Case Report: A Chronological Combination Treatment of Icotinib, Osimertinib, and Crizotinib on Lung Adenocarcinoma Guided by Serial Genetic Tests of Circulating Tumor DNA and Sediment Cell Genomic DNA From Pleural Effusion

Case Report: A Chronological Combination Treatment of Icotinib, Osimertinib, and Crizotinib on Lung Adenocarcinoma Guided by Serial Genetic Tests of Circulating Tumor DNA and Sediment Cell Genomic DNA From Pleural Effusion

Precision medicine has been getting more attention in lung cancer treatment. Here, we report an unusual case of a 71-year-old Chinese male patient with poorly differentiated lung adenocarcinoma with lymph node metastasis. A 5 years' treatment history of this patient is reported. By serial genet...

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Bibliographic Details
Main Authors: Zhihua Miao, Tianhao Mu, Longying Liu, Jingjie Rao, Min Jin, Zhizheng Wang, Hui Wang, Chao Lu, Xiaolin Gong, Dongcai Zheng, Daoming Zheng, Xin Li, Yingmei Li, Shifu Chen, Xinhua Shu
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Oncology
Subjects:
lung adenocarcinoma
serial genetic monitoring
EGFR mutation
MET amplification
ctDNA and PE-sDNA
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.561341/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2020.561341/full

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