Von Willebrand Factor Mediates Pneumococcal Aggregation and Adhesion in Blood Flow

Von Willebrand Factor Mediates Pneumococcal Aggregation and Adhesion in Blood Flow

Streptococcus pneumoniae is a major cause of community acquired pneumonia and septicaemia in humans. These diseases are frequently associated with thromboembolic cardiovascular complications. Pneumococci induce the exocytosis of endothelial Weibel-Palade Bodies and thereby actively stimulate the rel...

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Bibliographic Details
Main Authors: Hilger Jagau, Ina-Kristin Behrens, Karen Lahme, Georgina Lorz, Reinhard W. Köster, Reinhard Schneppenheim, Tobias Obser, Maria A. Brehm, Gesa König, Thomas P. Kohler, Manfred Rohde, Ronald Frank, Werner Tegge, Marcus Fulde, Sven Hammerschmidt, Michael Steinert, Simone Bergmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-03-01
Series:Frontiers in Microbiology
Subjects:
endothelium
von Willebrand factor
enolase
Streptococcus pneumoniae
zebrafish
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.00511/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.00511/full

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