Transmembrane recognition of the semaphorin co-receptors neuropilin 1 and plexin A1: coarse-grained simulations.

Transmembrane recognition of the semaphorin co-receptors neuropilin 1 and plexin A1: coarse-grained simulations.

The cancer associated class 3 semaphorins require direct binding to neuropilins and association to plexins to trigger cell signaling. Here, we address the role of the transmembrane domains of neuropilin 1 and plexin A1 for the dimerization of the two receptors by characterizing the assembly in lipid...

Full description

Bibliographic Details
Main Authors: Samia Aci-Sèche, Paul Sawma, Pierre Hubert, James N Sturgis, Dominique Bagnard, Laurent Jacob, Monique Genest, Norbert Garnier
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4032258?pdf=render

Internet

http://europepmc.org/articles/PMC4032258?pdf=render

Similar Items