The essentiality landscape of cell cycle related genes in human pluripotent and cancer cells
Abstract Background Cell cycle regulation is a complex system consisting of growth-promoting and growth-restricting mechanisms, whose coordinated activity is vital for proper division and propagation. Alterations in this regulation may lead to uncontrolled proliferation and genomic instability, trig...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
BMC
2019-12-01
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| Series: | Cell Division |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13008-019-0058-4 |