Correlated inter-domain motions in adenylate kinase.

Correlated inter-domain motions in adenylate kinase.

Correlated inter-domain motions in proteins can mediate fundamental biochemical processes such as signal transduction and allostery. Here we characterize at structural level the inter-domain coupling in a multidomain enzyme, Adenylate Kinase (AK), using computational methods that exploit the shape i...

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Bibliographic Details
Main Authors: Santiago Esteban-Martín, Robert Bryn Fenwick, Jörgen Ådén, Benjamin Cossins, Carlos W Bertoncini, Victor Guallar, Magnus Wolf-Watz, Xavier Salvatella
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-07-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC4117416?pdf=render

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http://europepmc.org/articles/PMC4117416?pdf=render

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