Correlated inter-domain motions in adenylate kinase.
Correlated inter-domain motions in proteins can mediate fundamental biochemical processes such as signal transduction and allostery. Here we characterize at structural level the inter-domain coupling in a multidomain enzyme, Adenylate Kinase (AK), using computational methods that exploit the shape i...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-07-01
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Series: | PLoS Computational Biology |
Online Access: | http://europepmc.org/articles/PMC4117416?pdf=render |