Protein-Bound Uremic Toxins in Hemodialysis Patients Relate to Residual Kidney Function, Are Not Influenced by Convective Transport, and Do Not Relate to Outcome

Protein-Bound Uremic Toxins in Hemodialysis Patients Relate to Residual Kidney Function, Are Not Influenced by Convective Transport, and Do Not Relate to Outcome

Protein-bound uremic toxins (PBUTs) are predominantly excreted by renal tubular secretion and hardly removed by traditional hemodialysis (HD). Accumulation of PBUTs is proposed to contribute to the increased morbidity and mortality of patients with end-stage kidney disease (ESKD). Preserved PBUT exc...

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Bibliographic Details
Main Authors: Maaike K. van Gelder, Igor R. Middel, Robin W. M. Vernooij, Michiel L. Bots, Marianne C. Verhaar, Rosalinde Masereeuw, Muriel P. Grooteman, Menso J. Nubé, M. A. van den Dorpel, Peter J. Blankestijn, Maarten B. Rookmaaker, Karin G.F. Gerritsen
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Toxins
Subjects:
End-stage kidney disease
Protein-bound uremic toxin
hemodialysis
hemodiafiltration
convection
residual kidney function
Online Access:https://www.mdpi.com/2072-6651/12/4/234

Internet

https://www.mdpi.com/2072-6651/12/4/234

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