The effect of aging on the repeated-dose liver micronucleus assay

Abstract Background The liver micronucleus (MN) assay is an effective and important in vivo test for detecting genotoxic compounds. In particular, the repeated-dose liver MN (RDLMN) assay which greatly facilitates incorporation of the liver MN assay into the general toxicity study has been developed...

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Bibliographic Details
Main Authors: Miyuki Shigano, Hironao Takasawa, Shuichi Hamada
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Genes and Environment
Subjects:
Online Access:https://doi.org/10.1186/s41021-021-00212-3