Genetic Contribution to Initial and Progressive Alcohol Intake Among Recombinant Inbred Strains of Mice

Genetic Contribution to Initial and Progressive Alcohol Intake Among Recombinant Inbred Strains of Mice

We profiled individual differences in alcohol consumption upon initial exposure and during 5 weeks of voluntary alcohol intake in female mice from 39 BXD recombinant inbred strains and parents using the drinking in the dark (DID) method. In this paradigm, a single bottle of 20% (v/v) alcohol was pre...

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Bibliographic Details
Main Authors: Megan K. Mulligan, Wenyuan Zhao, Morgan Dickerson, Danny Arends, Pjotr Prins, Sonia A. Cavigelli, Elena Terenina, Pierre Mormede, Lu Lu, Byron C. Jones
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-09-01
Series:Frontiers in Genetics
Subjects:
BXD
DID
QTL
alcoholism
alcohol intake
genetic variation
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2018.00370/full

Internet

https://www.frontiersin.org/article/10.3389/fgene.2018.00370/full

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