A Minimally-invasive Blood-derived Biomarker of Oligodendrocyte Cell-loss in Multiple Sclerosis

A Minimally-invasive Blood-derived Biomarker of Oligodendrocyte Cell-loss in Multiple Sclerosis

Multiple sclerosis (MS) is a neurodegenerative disease of the central nervous system (CNS). Minimally invasive biomarkers of MS are required for disease diagnosis and treatment. Differentially methylated circulating-free DNA (cfDNA) is a useful biomarker for disease diagnosis and prognosis, and may...

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Bibliographic Details
Main Authors: John A. Olsen, Lauren A. Kenna, Regine C. Tipon, Michael G. Spelios, Mark M. Stecker, Eitan M. Akirav
Format: Article
Language:English
Published: Elsevier 2016-08-01
Series:EBioMedicine
Subjects:
Relapsing-remitting multiple sclerosis
Oligodendrocyte
Cuprizone
Human patients
Circulating free DNA
Biomarker discovery
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396416302882

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http://www.sciencedirect.com/science/article/pii/S2352396416302882

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