Human Endogenous Retrovirus Expression Is Upregulated in the Breast Cancer Microenvironment of HIV Infected Women: A Pilot Study

Human Endogenous Retrovirus Expression Is Upregulated in the Breast Cancer Microenvironment of HIV Infected Women: A Pilot Study

In people living with HIV (PLWH), chronic inflammation can lead to cancer initiation and progression, besides driving a dysregulated and diminished immune responsiveness. HIV infection also leads to increased transcription of Human Endogenous Retroviruses (HERVs), which could increase an inflammator...

Full description

Bibliographic Details
Main Authors: Gislaine Curty, Greta A. Beckerle, Luis P. Iñiguez, Robert L. Furler, Pedro S. de Carvalho, Jez L. Marston, Stephane Champiat, Jonas J. Heymann, Christopher E. Ormsby, Gustavo Reyes-Terán, Marcelo A. Soares, Douglas F. Nixon, Matthew L. Bendall, Fabio E. Leal, Miguel de Mulder Rougvie
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Oncology
Subjects:
breast cancer
HIV
human endogenous retrovirus
retrotranscriptome
microenvironment
formalin-fixed paraffin-embedded
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2020.553983/full

Internet

https://www.frontiersin.org/articles/10.3389/fonc.2020.553983/full

Similar Items