Evaluation of A(H1N1)pdm09 LAIV vaccine candidates stability and replication efficiency in primary human nasal epithelial cells

The recent reduction of live attenuated influenza vaccine (LAIV) effectiveness in multivalent formulations was particularly associated with the A(H1N1)pdm09 component. In the 2017 the WHO vaccine composition committee changed its recommendations for the A(H1N1)pdm09 component to include an A/Michiga...

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Main Authors: Svetlana Shcherbik, Nicholas Pearce, Paul Carney, Ekaterina Bazhenova, Natalie Larionova, Irina Kiseleva, Larisa Rudenko, Amrita Kumar, Cynthia S. Goldsmith, Vivien Dugan, James Stevens, David E. Wentworth, Tatiana Bousse
Format: Article
Language:English
Published: Elsevier 2019-08-01
Series:Vaccine: X
Online Access:http://www.sciencedirect.com/science/article/pii/S2590136219300324