Aspartate-β-hydroxylase (ASPH): A potential therapeutic target in human malignant gliomas

Aspartate-β-hydroxylase (ASPH): A potential therapeutic target in human malignant gliomas

Background: Despite therapeutic advances, survival with glioblastoma multiforme (GBM) remains below 15 months from diagnosis due to GBM’s highly infiltrative nature which precludes complete surgical resection. Patient outcomes could potentially be improved by targeting genes and pathways that drive...

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Bibliographic Details
Main Authors: Lisa-Marie Sturla, Ming Tong, Nick Hebda, Jinsong Gao, John-Michael Thomas, Mark Olsen, Suzanne M. de la Monte
Format: Article
Language:English
Published: Elsevier 2016-12-01
Series:Heliyon
Subjects:
Medicine
Cell biology
Genetics
Neuroscience
Cancer Research
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844016303206

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http://www.sciencedirect.com/science/article/pii/S2405844016303206

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