Oligodendrocyte Nf1 Controls Aberrant Notch Activation and Regulates Myelin Structure and Behavior

Oligodendrocyte Nf1 Controls Aberrant Notch Activation and Regulates Myelin Structure and Behavior

Summary: The RASopathy neurofibromatosis type 1 (NF1) is one of the most common autosomal dominant genetic disorders. In NF1 patients, neurological issues may result from damaged myelin, and mice with a neurofibromin gene (Nf1) mutation show white matter (WM) defects including myelin decompaction. U...

Full description

Bibliographic Details
Main Authors: Alejandro López-Juárez, Haley E. Titus, Sadiq H. Silbak, Joshua W. Pressler, Tilat A. Rizvi, Madeleine Bogard, Michael R. Bennett, Georgianne Ciraolo, Michael T. Williams, Charles V. Vorhees, Nancy Ratner
Format: Article
Language:English
Published: Elsevier 2017-04-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124717304503

Internet

http://www.sciencedirect.com/science/article/pii/S2211124717304503

Similar Items