Early Moderate Intensity Aerobic Exercise Intervention Prevents Doxorubicin-Caused Cardiac Dysfunction Through Inhibition of Cardiac Fibrosis and Inflammation

Early Moderate Intensity Aerobic Exercise Intervention Prevents Doxorubicin-Caused Cardiac Dysfunction Through Inhibition of Cardiac Fibrosis and Inflammation

Doxorubicin (DOX) is known as an effective drug in the fight against various cancers. However, one of the greatest impediments is DOX-induced cardiomyopathy, which may potentially lead to heart failure. Accumulating evidence has shed light on the pathological mechanism of DOX-induced cardiotoxicity,...

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Bibliographic Details
Main Authors: Hsin-Lun Yang, Pei-Ling Hsieh, Ching-Hsia Hung, Hui-Ching Cheng, Wan-Ching Chou, Pei-Ming Chu, Yun-Ching Chang, Kun-Ling Tsai
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Cancers
Subjects:
doxorubicin
cardiac toxicity
cardiomyocytes
cardiac fibrosis
Online Access:https://www.mdpi.com/2072-6694/12/5/1102

Internet

https://www.mdpi.com/2072-6694/12/5/1102

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