Amyloidogenic and non-amyloidogenic transthyretin variants interact differently with human cardiomyocytes: insights into early events of non-fibrillar tissue damage
TTR (transthyretin) amyloidoses are diseases characterized by the aggregation and extracellular deposition of the normally soluble plasma protein TTR. Ex vivo and tissue culture studies suggest that tissue damage precedes TTR fibril deposition, indicating that early events in the amyloidogenic casc...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Portland Press, Biochemical Society
2015-01-01
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| Series: | Bioscience Reports |
| Subjects: | |
| Online Access: | http://www.bioscirep.org/bsr/035/e172/bsr035e172.htm |