Fenofibrate, a ligand for PPARα, inhibits aromatase cytochrome P450 expression in the ovary of mouse

Peroxisome proliferator-activated receptors (PPARs) play important roles in the metabolic regulation of lipids including steroids. In this study, we investigated whether fenofibrate, a ligand for PPARα, could influence estrogen synthesis in vivo in the ovary of mice. As reported, chronic treatment o...

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Bibliographic Details
Main Authors: Katsumi Toda, Teruhiko Okada, Chisata Miyaura, Toshiji Saibara
Format: Article
Language:English
Published: Elsevier 2003-02-01
Series:Journal of Lipid Research
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S002222752031213X