Synthesis and antitumor activity of novel indole derivatives containing α-aminophosphonate moieties

A series of novel indole derivatives containing α-aminophosphonate moieties were synthesized as antitumor agents. The in vitro cytotoxic activity of the compounds was evaluated against human hepatoma cells (HepG2) and human gastric cancer cells (MGC-803) by MTT assay, revealing that most of target c...

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Bibliographic Details
Main Authors: Jiaoli Ma, Jing Li, Penghu Guo, Xincheng Liao, Huicheng Cheng
Format: Article
Language:English
Published: Elsevier 2021-08-01
Series:Arabian Journal of Chemistry
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535221002719