The bacterial virulence factor CagA induces microbial dysbiosis that contributes to excessive epithelial cell proliferation in the Drosophila gut.

Gut microbiota facilitate many aspects of human health and development, but dysbiotic microbiota can promote hyperplasia and inflammation and contribute to human diseases such as cancer. Human patients infected with the gastric cancer-causing bacterium Helicobacter pylori have altered microbiota; ho...

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Bibliographic Details
Main Authors: Tiffani Alvey Jones, Diane Z Hernandez, Zoë C Wong, Anica M Wandler, Karen Guillemin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-10-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5648253?pdf=render