Oncolytic Newcastle Disease Virus as Cutting Edge between Tumor and Host

Oncolytic viruses (OVs) replicate selectively in tumor cells and exert anti-tumor cytotoxic activity. Among them, Newcastle Disease Virus (NDV), a bird RNA virus of the paramyxovirus family, appears outstanding. Its anti-tumor effect is based on: (i) oncolytic activity and (ii) immunostimulation. To...

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Bibliographic Details
Main Authors: Philippe Fournier, Volker Schirrmacher
Format: Article
Language:English
Published: MDPI AG 2013-07-01
Series:Biology
Subjects:
Online Access:http://www.mdpi.com/2079-7737/2/3/936