Conserved immune recognition hierarchy of mycobacterial PE/PPE proteins during infection in natural hosts.

Conserved immune recognition hierarchy of mycobacterial PE/PPE proteins during infection in natural hosts.

The Mycobacterium tuberculosis genome contains two large gene families encoding proteins of unknown function, characterized by conserved N-terminal proline and glutamate (PE and PPE) motifs. The presence of a large number of PE/PPE proteins with repetitive domains and evidence of strain variation ha...

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Bibliographic Details
Main Authors: H Martin Vordermeier, R Glyn Hewinson, Robert J Wilkinson, Katalin A Wilkinson, Hannah P Gideon, Douglas B Young, Samantha L Sampson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3411574?pdf=render

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http://europepmc.org/articles/PMC3411574?pdf=render

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