Report of a germline double heterozygote in MSH2 and PALB2

Report of a germline double heterozygote in MSH2 and PALB2

Abstract Background Carriers with pathogenic variants in MSH2 have increased risk to develop colorectal, endometrium, ovarian, and other types of cancer. The PALB2 is associated with breast, ovarian, pancreatic, and prostate cancer. We describe the case of a 42‐year‐old female diagnosed with endomet...

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Bibliographic Details
Main Authors: Konstantinos Agiannitopoulos, Eirini Papadopoulou, Georgios N. Tsaousis, Georgia Pepe, Stavroula Kampouri, Eleni Patsea, George Lypas, George Nasioulas
Format: Article
Language:English
Published: Wiley 2020-10-01
Series:Molecular Genetics & Genomic Medicine
Subjects:
endometrial cancer
MSH2
NGS
PALB2
pathogenic variant
Online Access:https://doi.org/10.1002/mgg3.1242

Internet

https://doi.org/10.1002/mgg3.1242

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