DNM1L-Related Mitochondrial Fission Defects Presenting as Encephalopathy: A Case Report and Literature Review

DNM1L-Related Mitochondrial Fission Defects Presenting as Encephalopathy: A Case Report and Literature Review

Background: Mitochondrial dynamics, including mitochondrial fission and fusion, transport and distribution, biogenesis and degradation, are critical to neuronal function. The dynamin-1 like (DNM1L) gene encodes dynamin-related protein 1 (DRP1/DLP1), which is an evolutionarily conserved member of the...

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Bibliographic Details
Main Authors: Xingmiao Liu, Zhongbin Zhang, Dong Li, Meifang Lei, Qing Li, Xiaojun Liu, Peiyuan Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Pediatrics
Subjects:
DNM1L
DRP1
mitochondrial disease
psychomotor retardation
dyskinesia
hypertonia
Online Access:https://www.frontiersin.org/articles/10.3389/fped.2021.626657/full

Internet

https://www.frontiersin.org/articles/10.3389/fped.2021.626657/full

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