Temporospatial induction of homeodomain gene cut dictates natural lineage reprogramming

Understanding how cellular identity naturally interconverts with high efficiency and temporospatial precision is crucial for regenerative medicine. Here, we revealed a natural midgut-to-renal lineage conversion event during Drosophila metamorphosis and identified the evolutionarily-conserved homeodo...

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Bibliographic Details
Main Authors: Ke Xu, Xiaodan Liu, Yuchun Wang, Chouin Wong, Yan Song
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-05-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/33934