Association of Common Variations on Chromosome 4q25 and Left Atrial Volume in Patients with Atrial Fibrillation

Aims Recent studies have shown that several genetic variants near the PITX2 locus on chromosome 4q25 are associated with atrial fibrillation (AF). However, the mechanism that mediates this association remains unclear. Basic murine studies suggest that reduced PITX2 expression is associated with left...

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Bibliographic Details
Main Authors: Yuliya Mints, Hirad Yarmohammadi, Irfan M. Khurram, Hana Hoyt, Rozann Hansford, Stefan L. Zimmerman, Steven J. Steinberg, Daniel P. Judge, Gordon F. Tomaselli, Hugh Calkins, Vadim Zipunnikov, Saman Nazarian
Format: Article
Language:English
Published: SAGE Publishing 2015-01-01
Series:Clinical Medicine Insights: Cardiology
Online Access:https://doi.org/10.4137/CMC.S21712