Approaches to Improve Chemically Defined Synthetic Peptide Vaccines

Approaches to Improve Chemically Defined Synthetic Peptide Vaccines

Progress made in peptide-based vaccinations to induce T-cell-dependent immune responses against cancer has invigorated the search for optimal vaccine modalities. Design of new vaccine strategies intrinsically depends on the knowledge of antigen handling and optimal epitope presentation in both major...

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Bibliographic Details
Main Authors: Brett J. Hos, Elena Tondini, Sander I. van Kasteren, Ferry Ossendorp
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-04-01
Series:Frontiers in Immunology
Subjects:
peptide vaccination
click chemistry
antigen presentation
intracellular processing
targeted vaccination
tumor immunology
Online Access:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00884/full

Internet

http://journal.frontiersin.org/article/10.3389/fimmu.2018.00884/full

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