Mutant three-repeat tau expression initiates retinal ganglion cell death through Caspase-2
The microtubule-associated protein tau is implicated in multiple degenerative diseases including retinal diseases such as glaucoma; however, the way tau initiates retinopathy is unclear. Previous retinal assessments in mouse models of tauopathy suggest that mutations in four-repeat (4R) tau are asso...
Main Authors: | Jennifer Ngolab, Saranya Canchi, Suhail Rasool, Abderrahman Elmaarouf, Kimberly Thomas, Floyd Sarsoza, Jennifer Grundman, Michael Mante, Jazmin Florio, Nimisha Nandankar, Shaina Korouri, Wagner Zago, Eliezer Masliah, Robert A. Rissman |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2021-05-01
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Series: | Neurobiology of Disease |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0969996121000267 |
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