α2-Antiplasmin as a potential regulator of the spatial memory process and age-related cognitive decline

Abstract α2-Antiplasmin (α2AP), a principal physiological plasmin inhibitor, is mainly produced by the liver and kidneys, but it is also expressed in several parts of the brain, including the hippocampus and cerebral cortex. Our previous study demonstrated that α2AP knockout mice exhibit spatial mem...

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Bibliographic Details
Main Authors: Eri Kawashita, Keiichi Ishihara, Haruko Miyaji, Yu Tanishima, Akiko Kiriyama, Osamu Matsuo, Satoshi Akiba
Format: Article
Language:English
Published: BMC 2020-10-01
Series:Molecular Brain
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13041-020-00677-3