SARS-CoV-2 and interferon blockade

Abstract The response to viral infection generally includes an activation of the adaptive immune response to produce cytotoxic T cells and neutralizing antibodies. We propose that SARS-CoV-2 activates the innate immune system through the renin-angiotensin and kallikrein-bradykinin pathways, blocks i...

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Bibliographic Details
Main Authors: Betty Diamond, Bruce T. Volpe, Sonya VanPatten, Yousef Al Abed
Format: Article
Language:English
Published: BMC 2020-11-01
Series:Molecular Medicine
Online Access:http://link.springer.com/article/10.1186/s10020-020-00231-w