Signal recognition particle and SecA cooperate during export of secretory proteins with highly hydrophobic signal sequences.

The Sec translocon of bacterial plasma membranes mediates the linear translocation of secretory proteins as well as the lateral integration of membrane proteins. Integration of many membrane proteins occurs co-translationally via the signal recognition particle (SRP)-dependent targeting of ribosome-...

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Bibliographic Details
Main Authors: Yufan Zhou, Takuya Ueda, Matthias Müller
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3981701?pdf=render