Mouse models of SCN5A-related cardiac arrhythmias

Mouse models of SCN5A-related cardiac arrhythmias

Mutations of SCN5A gene, which encodes the α-subunit of the voltage-gated Na+ channel NaV1.5, underlie hereditary cardiac arrhythmic syndromes such as the type 3 long QT syndrome, cardiac conduction diseases, the Brugada syndrome, the sick sinus syndrome, atrial standstill and numerous overlap syndr...

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Bibliographic Details
Main Authors: Flavien eCharpentier, Mickael eDerangeon, Jérôme eMontnach, Isabelle eBaró
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-06-01
Series:Frontiers in Physiology
Subjects:
Brugada Syndrome
Long QT Syndrome
arrhythmia
Nav1.5
conduction disease
sinus node dysfunction
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00210/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00210/full

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