Understanding the Pathophysiology of COVID-19: Could the Contact System Be the Key?

Understanding the Pathophysiology of COVID-19: Could the Contact System Be the Key?

To date the pathophysiology of COVID-19 remains unclear: this represents a factor determining the current lack of effective treatments. In this paper, we hypothesized a complex host response to SARS-CoV-2, with the Contact System (CS) playing a pivotal role in innate immune response. CS is linked wi...

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Bibliographic Details
Main Authors: Simone Meini, Andrea Zanichelli, Rodolfo Sbrojavacca, Federico Iuri, Anna Teresa Roberts, Chiara Suffritti, Carlo Tascini
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-08-01
Series:Frontiers in Immunology
Subjects:
SARS-CoV-2
COVID-19
pathophysiology
Contact System
bradykinin
ACE
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.02014/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2020.02014/full

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