New horizons in the roles and associations of COX-2 and novel natural inhibitors in cardiovascular diseases

Abstract Age-related cardiovascular disease is the leading cause of death in elderly populations. Coxibs, including celecoxib, valdecoxib, etoricoxib, parecoxib, lumiracoxib, and rofecoxib, are selective cyclooxygenase-2 (COX-2) inhibitors used to treat osteoarthritis and rheumatoid arthritis. Howev...

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Bibliographic Details
Main Authors: Wujun Chen, Yingjie Zhong, Nuan Feng, Zhu Guo, Shuai Wang, Dongming Xing
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Molecular Medicine
Subjects:
Online Access:https://doi.org/10.1186/s10020-021-00358-4