Pre-pregnancy BMI-associated miRNA and mRNA expression signatures in the placenta highlight a sexually-dimorphic response to maternal underweight status

Abstract Pre-pregnancy body mass index (BMI) is associated with adverse pregnancy and neonatal health outcomes, with differences in risk observed between sexes. Given that the placenta is a sexually dimorphic organ and critical regulator of development, examining differences in placental mRNA and mi...

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Bibliographic Details
Main Authors: Jeliyah Clark, Lauren A. Eaves, Adriana R. Gaona, Hudson P. Santos, Lisa Smeester, Jacqueline T. Bangma, Julia E. Rager, T. Michael O’Shea, Rebecca C. Fry
Format: Article
Language:English
Published: Nature Publishing Group 2021-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-95051-1