Design, construction, and analysis of specific zinc finger nucleases for microphthalmia - associate transcription factor

This work studied the design, construction, and cleavage analysis of zinc finger nucleases (ZFNs) that could cut the specific sequences within microphthalmia - associate transcription factor (mitfa) of zebra fish. The target site and ZFPs were selected and designed with zinc finger tools, while the...

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Bibliographic Details
Main Authors: Wenwen Wang, Hongmao Liu, Haibin Zhao, Zaili Luo, Yongxiang Shi
Format: Article
Language:English
Published: Instituto de Tecnologia do Paraná (Tecpar) 2012-08-01
Series:Brazilian Archives of Biology and Technology
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1516-89132012000400011