Tetrahydrocannabinol Induces Brain Mitochondrial Respiratory Chain Dysfunction and Increases Oxidative Stress: A Potential Mechanism Involved in Cannabis-Related Stroke

Tetrahydrocannabinol Induces Brain Mitochondrial Respiratory Chain Dysfunction and Increases Oxidative Stress: A Potential Mechanism Involved in Cannabis-Related Stroke

Cannabis has potential therapeutic use but tetrahydrocannabinol (THC), its main psychoactive component, appears as a risk factor for ischemic stroke in young adults. We therefore evaluate the effects of THC on brain mitochondrial function and oxidative stress, key factors involved in stroke. Maximal...

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Bibliographic Details
Main Authors: Valérie Wolff, Anna-Isabel Schlagowski, Olivier Rouyer, Anne-Laure Charles, François Singh, Cyril Auger, Valérie Schini-Kerth, Christian Marescaux, Jean-Sébastien Raul, Joffrey Zoll, Bernard Geny
Format: Article
Language:English
Published: Hindawi Limited 2015-01-01
Series:BioMed Research International
Online Access:http://dx.doi.org/10.1155/2015/323706

Internet

http://dx.doi.org/10.1155/2015/323706

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