Inflammatory, synaptic, motor, and behavioral alterations induced by gestational sepsis on the offspring at different stages of life

Inflammatory, synaptic, motor, and behavioral alterations induced by gestational sepsis on the offspring at different stages of life

Abstract Background The term sepsis is used to designate a systemic condition of infection and inflammation associated with hemodynamic changes that result in organic dysfunction. Gestational sepsis can impair the development of the central nervous system and may promote permanent behavior alteratio...

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Bibliographic Details
Main Authors: Marcelo Gomes Granja, Letícia Pires Alves, Marina Leardini-Tristão, Michelle Edelman Saul, Letícia Coelho Bortoni, Flávia Maciel de Moraes, Erica Camila Ferreira, Bianca Portugal Tavares de Moraes, Victória Zerboni da Silva, Adrielle Ferreira Ribeiro dos Santos, Adriana Ribeiro Silva, Cassiano Felippe Gonçalves-de-Albuquerque, Victorio Bambini-Junior, Andrew S. Weyrich, Matthew T. Rondina, Guy A. Zimmerman, Hugo Caire de Castro-Faria-Neto
Format: Article
Language:English
Published: BMC 2021-02-01
Series:Journal of Neuroinflammation
Subjects:
Gestational sepsis
Synaptophysin
Depression
Memory
Motor damage
Online Access:https://doi.org/10.1186/s12974-021-02106-1

Internet

https://doi.org/10.1186/s12974-021-02106-1

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