MatCol: a tool to measure fluorescence signal colocalisation in biological systems

Abstract Protein colocalisation is often studied using pixel intensity-based coefficients such as Pearson, Manders, Li or Costes. However, these methods cannot be used to study object-based colocalisations in biological systems. Therefore, a novel method is required to automatically identify regions...

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Bibliographic Details
Main Authors: Matloob Khushi, Christine E. Napier, Christine M. Smyth, Roger R. Reddel, Jonathan W. Arthur
Format: Article
Language:English
Published: Nature Publishing Group 2017-08-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-017-08786-1